Functional and Structural Characterization of OXA-935, a Novel OXA-10-Family β-Lactamase from Pseudomonas aeruginosa

Resistance to antipseudomonal penicillins and cephalosporins is often driven by the overproduction of the intrinsic β-lactamase AmpC. However, OXA-10-family β-lactamases are a rich source of resistance in Pseudomonas aeruginosa. OXA β-lactamases have a propensity for mutation that leads to extended...

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Detalles Bibliográficos
Autores principales: Pincus, Nathan B., Rosas-Lemus, Monica, Gatesy, Samuel W. M., Bertucci, Hanna K., Brunzelle, Joseph S., Minasov, George, Shuvalova, Ludmilla A., Lebrun-Corbin, Marine, Satchell, Karla J. F., Ozer, Egon A., Hauser, Alan R., Bachta, Kelly E. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Mechanisms of Resistance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578422/
https://www.ncbi.nlm.nih.gov/pubmed/36129295
http://dx.doi.org/10.1128/aac.00985-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578422/
https://www.ncbi.nlm.nih.gov/pubmed/36129295
http://dx.doi.org/10.1128/aac.00985-22

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