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Functional and Structural Characterization of OXA-935, a Novel OXA-10-Family β-Lactamase from Pseudomonas aeruginosa

Resistance to antipseudomonal penicillins and cephalosporins is often driven by the overproduction of the intrinsic β-lactamase AmpC. However, OXA-10-family β-lactamases are a rich source of resistance in Pseudomonas aeruginosa. OXA β-lactamases have a propensity for mutation that leads to extended...

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Detalles Bibliográficos
Autores principales:	Pincus, Nathan B., Rosas-Lemus, Monica, Gatesy, Samuel W. M., Bertucci, Hanna K., Brunzelle, Joseph S., Minasov, George, Shuvalova, Ludmilla A., Lebrun-Corbin, Marine, Satchell, Karla J. F., Ozer, Egon A., Hauser, Alan R., Bachta, Kelly E. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Mechanisms of Resistance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578422/ https://www.ncbi.nlm.nih.gov/pubmed/36129295 http://dx.doi.org/10.1128/aac.00985-22

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