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Unambiguous identification of α-Gal epitopes in intact monoclonal antibodies by NMR spectroscopy

The α-Gal epitope consisting of the terminal trisaccharide Galα1,3Galβ1,4GlcNAc exposed on cell or protein surfaces can cause severe immune reactions, such as hypersensitivity reactions, in humans. This epitope is also called the xenotransplantation epitope because it is one of the main reasons for...

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Detalles Bibliográficos
Autores principales: Hinterholzer, Arthur, Moises, Jennifer, Regl, Christof, Schwap, Sebastian, Rapp, Erdmann, Huber, Christian G., Schubert, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578466/
https://www.ncbi.nlm.nih.gov/pubmed/36239533
http://dx.doi.org/10.1080/19420862.2022.2132977