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Unambiguous identification of α-Gal epitopes in intact monoclonal antibodies by NMR spectroscopy
The α-Gal epitope consisting of the terminal trisaccharide Galα1,3Galβ1,4GlcNAc exposed on cell or protein surfaces can cause severe immune reactions, such as hypersensitivity reactions, in humans. This epitope is also called the xenotransplantation epitope because it is one of the main reasons for...
Autores principales: | Hinterholzer, Arthur, Moises, Jennifer, Regl, Christof, Schwap, Sebastian, Rapp, Erdmann, Huber, Christian G., Schubert, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578466/ https://www.ncbi.nlm.nih.gov/pubmed/36239533 http://dx.doi.org/10.1080/19420862.2022.2132977 |
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