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Angiotensin II type 2 receptor prevents extracellular matrix accumulation in human peritoneal mesothelial cell by ameliorating lipid disorder via LOX‐1 suppression

Evidence suggests that intracellular angiotensin II type 1 receptor (AT1) contributes to peritoneal fibrosis (PF) under high glucose (HG)-based dialysates. It is generally believed that AT2 antagonisticly affects AT1 function. The aim of this study was to explore whether AT2 activation is beneficial...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Jin, Bo, Lu, Jian, Feng, Yuan, Li, Nan, Wan, Cheng, Zhang, Qing-Yan, Jiang, Chun-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578471/
https://www.ncbi.nlm.nih.gov/pubmed/36226438
http://dx.doi.org/10.1080/0886022X.2022.2133729