Targeting depletion of myeloid-derived suppressor cells potentiates PD-L1 blockade efficacy in gastric and colon cancers

Myeloid-derived suppressor cells (MDSCs) have been demonstrated to suppress antitumor immunity and induce resistance to PD-1/PD-L1 blockade immunotherapy in gastric and colon cancer patients. Herein, we found that MDSCs accumulate in mice bearing syngeneic gastric cancer and colon cancer. Death rece...

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Detalles Bibliográficos
Autores principales: Tang, Yao, Zhou, Cong, Li, Qingli, Cheng, Xiaojiao, Huang, Tinglei, Li, Fuli, He, Lina, Zhang, Baiweng, Tu, Shuiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578486/
https://www.ncbi.nlm.nih.gov/pubmed/36268178
http://dx.doi.org/10.1080/2162402X.2022.2131084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578486/
https://www.ncbi.nlm.nih.gov/pubmed/36268178
http://dx.doi.org/10.1080/2162402X.2022.2131084

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