Linear discriminant analysis reveals hidden patterns in NMR chemical shifts of intrinsically disordered proteins

NMR spectroscopy is key in the study of intrinsically disordered proteins (IDPs). Yet, even the first step in such an analysis—the assignment of observed resonances to particular nuclei—is often problematic due to low peak dispersion in the spectra of IDPs. We show that the assignment process can be...

Descripción completa

Detalles Bibliográficos
Autores principales: Romero, Javier A., Putko, Paulina, Urbańczyk, Mateusz, Kazimierczuk, Krzysztof, Zawadzka-Kazimierczuk, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578625/
https://www.ncbi.nlm.nih.gov/pubmed/36201530
http://dx.doi.org/10.1371/journal.pcbi.1010258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578625/
https://www.ncbi.nlm.nih.gov/pubmed/36201530
http://dx.doi.org/10.1371/journal.pcbi.1010258

Ejemplares similares