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Linear discriminant analysis reveals hidden patterns in NMR chemical shifts of intrinsically disordered proteins
NMR spectroscopy is key in the study of intrinsically disordered proteins (IDPs). Yet, even the first step in such an analysis—the assignment of observed resonances to particular nuclei—is often problematic due to low peak dispersion in the spectra of IDPs. We show that the assignment process can be...
Autores principales: | Romero, Javier A., Putko, Paulina, Urbańczyk, Mateusz, Kazimierczuk, Krzysztof, Zawadzka-Kazimierczuk, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578625/ https://www.ncbi.nlm.nih.gov/pubmed/36201530 http://dx.doi.org/10.1371/journal.pcbi.1010258 |
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