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Airway basal cells show regionally distinct potential to undergo metaplastic differentiation

Basal cells are multipotent stem cells of a variety of organs, including the respiratory tract, where they are major components of the airway epithelium. However, it remains unclear how diverse basal cells are and how distinct subpopulations respond to airway challenges. Using single cell RNA-sequen...

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Detalles Bibliográficos
Autores principales: Zhou, Yizhuo, Yang, Ying, Guo, Lihao, Qian, Jun, Ge, Jian, Sinner, Debora, Ding, Hongxu, Califano, Andrea, Cardoso, Wellington V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578702/
https://www.ncbi.nlm.nih.gov/pubmed/36178196
http://dx.doi.org/10.7554/eLife.80083