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Poxviruses capture host genes by LINE-1 retrotransposition

Horizontal gene transfer (HGT) provides a major source of genetic variation. Many viruses, including poxviruses, encode genes with crucial functions directly gained by gene transfer from hosts. The mechanism of transfer to poxvirus genomes is unknown. Using genome analysis and experimental screens o...

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Detalles Bibliográficos
Autores principales: Fixsen, Sarah M, Cone, Kelsey R, Goldstein, Stephen A, Sasani, Thomas A, Quinlan, Aaron R, Rothenburg, Stefan, Elde, Nels C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578705/
https://www.ncbi.nlm.nih.gov/pubmed/36069526
http://dx.doi.org/10.7554/eLife.63332