Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury

The Hippo signaling pathway controls cell proliferation and tissue regeneration via its transcriptional effectors yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ). The canonical pathway topology is characterized by sequential phosphorylation of kinases in the...

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Detalles Bibliográficos
Autores principales: Wehling, Lilija, Keegan, Liam, Fernández-Palanca, Paula, Hassan, Reham, Ghallab, Ahmed, Schmitt, Jennifer, Tang, Yingyue, Le Marois, Maxime, Roessler, Stephanie, Schirmacher, Peter, Kummer, Ursula, Hengstler, Jan G, Sahle, Sven, Breuhahn, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578710/
https://www.ncbi.nlm.nih.gov/pubmed/36255405
http://dx.doi.org/10.7554/eLife.78540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578710/
https://www.ncbi.nlm.nih.gov/pubmed/36255405
http://dx.doi.org/10.7554/eLife.78540

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