Non-invasive classification of macrophage polarisation by 2P-FLIM and machine learning

In this study, we utilise fluorescence lifetime imaging of NAD(P)H-based cellular autofluorescence as a non-invasive modality to classify two contrasting states of human macrophages by proxy of their governing metabolic state. Macrophages derived from human blood-circulating monocytes were polarised...

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Detalles Bibliográficos
Autores principales: Neto, Nuno GB, O'Rourke, Sinead A, Zhang, Mimi, Fitzgerald, Hannah K, Dunne, Aisling, Monaghan, Michael G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578711/
https://www.ncbi.nlm.nih.gov/pubmed/36254592
http://dx.doi.org/10.7554/eLife.77373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578711/
https://www.ncbi.nlm.nih.gov/pubmed/36254592
http://dx.doi.org/10.7554/eLife.77373

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