Cargando…
Non-invasive classification of macrophage polarisation by 2P-FLIM and machine learning
In this study, we utilise fluorescence lifetime imaging of NAD(P)H-based cellular autofluorescence as a non-invasive modality to classify two contrasting states of human macrophages by proxy of their governing metabolic state. Macrophages derived from human blood-circulating monocytes were polarised...
Autores principales: | Neto, Nuno GB, O'Rourke, Sinead A, Zhang, Mimi, Fitzgerald, Hannah K, Dunne, Aisling, Monaghan, Michael G |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578711/ https://www.ncbi.nlm.nih.gov/pubmed/36254592 http://dx.doi.org/10.7554/eLife.77373 |
Ejemplares similares
-
The Role of Macrophages in the Infarcted Myocardium: Orchestrators of ECM Remodeling
por: O'Rourke, Sinead A., et al.
Publicado: (2019) -
The Trypanosoma brucei-Derived Ketoacids, Indole Pyruvate and Hydroxyphenylpyruvate, Induce HO-1 Expression and Suppress Inflammatory Responses in Human Dendritic Cells
por: Fitzgerald, Hannah K., et al.
Publicado: (2022) -
A deeper understanding of intestinal organoid metabolism revealed by combining fluorescence lifetime imaging microscopy (FLIM) and extracellular flux analyses
por: Okkelman, Irina A., et al.
Publicado: (2019) -
Effect of Phosphorylation on EGFR Dimer Stability Probed by Single-Molecule Dynamics and FRET/FLIM
por: Coban, Oana, et al.
Publicado: (2015) -
Environmental and Geographical (EG) Image Classification Using FLIM and CNN Algorithms
por: Ajay, P., et al.
Publicado: (2022)