Extracellular Vesicles Derived from Lung Cancer Cells Induce Transformation of Normal Fibroblasts into Lung Cancer-Associated Fibroblasts and Promote Metastasis of Lung Cancer by Delivering lncRNA HOTAIR

Human lung cancer (LC) cells A549/H358, normal lung epithelial cells BEAS-2B, and lung normal fibroblasts (NFs) were cultured, followed by transfection of H358 cells with HOTAIR shRNA. Extracellular vesicles (EVs) extracted from H358 cells were identified. The internalization of Dil-labeled-EVs by N...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoxuan, Zhang, Yan, Qiu, Xin, Cai, Jing, Yang, Zhenzhou, Song, Fangzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578906/
https://www.ncbi.nlm.nih.gov/pubmed/36267242
http://dx.doi.org/10.1155/2022/3805013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578906/
https://www.ncbi.nlm.nih.gov/pubmed/36267242
http://dx.doi.org/10.1155/2022/3805013

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