The orchestrated signaling by PI3Kα and PTEN at the membrane interface

The oncogene PI3Kα and the tumor suppressor PTEN represent two antagonistic enzymatic activities that regulate the interconversion of the phosphoinositide lipids PI(4,5)P(2) and PI(3,4,5)P(3) in membranes. As such, they are defining components of phosphoinositide-based cellular signaling and membran...

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Detalles Bibliográficos
Autores principales: Kotzampasi, Danai Maria, Premeti, Kyriaki, Papafotika, Alexandra, Syropoulou, Vasiliki, Christoforidis, Savvas, Cournia, Zoe, Leondaritis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Mini Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578963/
https://www.ncbi.nlm.nih.gov/pubmed/36284707
http://dx.doi.org/10.1016/j.csbj.2022.10.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578963/
https://www.ncbi.nlm.nih.gov/pubmed/36284707
http://dx.doi.org/10.1016/j.csbj.2022.10.007

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