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A siRNA screening of UBE2 family demonstrated that UBE2R1 had a high repressive effect on HIV Tat protein

HIV Tat is an essential protein required for the transcription elongation of HIV genome. It has been shown that Tat can be degraded by either proteasome or autophagy pathways. In this study, it was shown that proteasome inhibitor MG132 could significantly prevent HIV Tat protein degradation in Tat o...

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Detalles Bibliográficos
Autores principales: Xu, Muyu, Zhang, Jiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578976/
https://www.ncbi.nlm.nih.gov/pubmed/36275929
http://dx.doi.org/10.1016/j.bbrep.2022.101366