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A siRNA screening of UBE2 family demonstrated that UBE2R1 had a high repressive effect on HIV Tat protein
HIV Tat is an essential protein required for the transcription elongation of HIV genome. It has been shown that Tat can be degraded by either proteasome or autophagy pathways. In this study, it was shown that proteasome inhibitor MG132 could significantly prevent HIV Tat protein degradation in Tat o...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578976/ https://www.ncbi.nlm.nih.gov/pubmed/36275929 http://dx.doi.org/10.1016/j.bbrep.2022.101366 |