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XDec-CHI reveals immunosuppressive interactions in pancreatic ductal adenocarcinoma

Most cancers harbor a diverse collection of cell types including a typically heterogeneous cancer cell fraction. To reconstruct cell-intrinsic and heterotypic interactions driving tumor progression, we combine the XDec deconvolution method with cell-type-specific gene expression correlation analysis...

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Detalles Bibliográficos
Autores principales: LaPlante, Emily L., Liu, Dongliang, Petrosyan, Varduhi, Yao, Qizhi, Milosavljevic, Aleksandar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579012/
https://www.ncbi.nlm.nih.gov/pubmed/36274954
http://dx.doi.org/10.1016/j.isci.2022.105249