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XDec-CHI reveals immunosuppressive interactions in pancreatic ductal adenocarcinoma
Most cancers harbor a diverse collection of cell types including a typically heterogeneous cancer cell fraction. To reconstruct cell-intrinsic and heterotypic interactions driving tumor progression, we combine the XDec deconvolution method with cell-type-specific gene expression correlation analysis...
Autores principales: | LaPlante, Emily L., Liu, Dongliang, Petrosyan, Varduhi, Yao, Qizhi, Milosavljevic, Aleksandar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579012/ https://www.ncbi.nlm.nih.gov/pubmed/36274954 http://dx.doi.org/10.1016/j.isci.2022.105249 |
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