Chemotherapeutic drug screening in 3D-Bioengineered human myobundles provides insight into taxane-induced myotoxicities

Two prominent frontline breast cancer (BC) chemotherapies commonly used in combination, doxorubicin (DOX) and docetaxel (TAX), are associated with long-lasting cardiometabolic and musculoskeletal side effects. Whereas DOX has been linked to mitochondrial dysfunction, mechanisms underlying TAX-induce...

Descripción completa

Detalles Bibliográficos
Autores principales: Torres, Maria J., Zhang, Xu, Slentz, Dorothy H., Koves, Timothy R., Patel, Hailee, Truskey, George A., Muoio, Deborah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579017/
https://www.ncbi.nlm.nih.gov/pubmed/36274957
http://dx.doi.org/10.1016/j.isci.2022.105189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579017/
https://www.ncbi.nlm.nih.gov/pubmed/36274957
http://dx.doi.org/10.1016/j.isci.2022.105189

Ejemplares similares