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Death domain–associated protein DAXX regulates noncoding RNA transcription at the centromere through the transcription regulator ZFAT

The centromere is an essential chromosomal structure for faithful chromosome segregation during cell division. No protein-coding genes exist at the centromeres, but centromeric DNA is actively transcribed into noncoding RNA (ncRNA). This centromeric transcription and its ncRNA products play importan...

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Detalles Bibliográficos
Autores principales: Ishikura, Shuhei, Yoshida, Kazumasa, Tsunoda, Toshiyuki, Shirasawa, Senji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579039/
https://www.ncbi.nlm.nih.gov/pubmed/36162510
http://dx.doi.org/10.1016/j.jbc.2022.102528