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Network biology analysis of P23H rhodopsin interactome identifies protein and mRNA quality control mechanisms
Rhodopsin is essential for phototransduction, and many rhodopsin mutations cause heritable retinal degenerations. The P23H rhodopsin variant generates a misfolded rhodopsin protein that photoreceptors quickly target for degradation by mechanisms that are incompletely understood. To gain insight into...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579138/ https://www.ncbi.nlm.nih.gov/pubmed/36258031 http://dx.doi.org/10.1038/s41598-022-22316-8 |