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The hypoxia response pathway promotes PEP carboxykinase and gluconeogenesis in C. elegans

Actively dividing cells, including some cancers, rely on aerobic glycolysis rather than oxidative phosphorylation to generate energy, a phenomenon termed the Warburg effect. Constitutive activation of the Hypoxia Inducible Factor (HIF-1), a transcription factor known for mediating an adaptive respon...

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Detalles Bibliográficos
Autores principales: Vora, Mehul, Pyonteck, Stephanie M., Popovitchenko, Tatiana, Matlack, Tarmie L., Prashar, Aparna, Kane, Nanci S., Favate, John, Shah, Premal, Rongo, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579151/
https://www.ncbi.nlm.nih.gov/pubmed/36257965
http://dx.doi.org/10.1038/s41467-022-33849-x