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The hypoxia response pathway promotes PEP carboxykinase and gluconeogenesis in C. elegans
Actively dividing cells, including some cancers, rely on aerobic glycolysis rather than oxidative phosphorylation to generate energy, a phenomenon termed the Warburg effect. Constitutive activation of the Hypoxia Inducible Factor (HIF-1), a transcription factor known for mediating an adaptive respon...
Autores principales: | Vora, Mehul, Pyonteck, Stephanie M., Popovitchenko, Tatiana, Matlack, Tarmie L., Prashar, Aparna, Kane, Nanci S., Favate, John, Shah, Premal, Rongo, Christopher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579151/ https://www.ncbi.nlm.nih.gov/pubmed/36257965 http://dx.doi.org/10.1038/s41467-022-33849-x |
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