Druggable transcriptomic pathways revealed in Parkinson’s patient-derived midbrain neurons

Complex genetic predispositions accelerate the chronic degeneration of midbrain substantia nigra neurons in Parkinson’s disease (PD). Deciphering the human molecular makeup of PD pathophysiology can guide the discovery of therapeutics to slow the disease progression. However, insights from human pos...

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Detalles Bibliográficos
Autores principales: van den Hurk, Mark, Lau, Shong, Marchetto, Maria C., Mertens, Jerome, Stern, Shani, Corti, Olga, Brice, Alexis, Winner, Beate, Winkler, Jürgen, Gage, Fred H., Bardy, Cedric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579158/
https://www.ncbi.nlm.nih.gov/pubmed/36258029
http://dx.doi.org/10.1038/s41531-022-00400-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579158/
https://www.ncbi.nlm.nih.gov/pubmed/36258029
http://dx.doi.org/10.1038/s41531-022-00400-0

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