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A simple thermodynamic description of phase separation of Nup98 FG domains

The permeability barrier of nuclear pore complexes (NPCs) controls nucleocytoplasmic transport. It retains inert macromolecules but allows facilitated passage of nuclear transport receptors that shuttle cargoes into or out of nuclei. The barrier can be described as a condensed phase assembled from c...

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Detalles Bibliográficos
Autores principales: Ng, Sheung Chun, Görlich, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579204/
https://www.ncbi.nlm.nih.gov/pubmed/36257947
http://dx.doi.org/10.1038/s41467-022-33697-9