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Generation and maturation of human iPSC-derived 3D organotypic cardiac microtissues in long-term culture

Cardiovascular diseases remain the leading cause of death worldwide; hence there is an increasing focus on developing physiologically relevant in vitro cardiovascular tissue models suitable for studying personalized medicine and pre-clinical tests. Despite recent advances, models that reproduce both...

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Detalles Bibliográficos
Autores principales: Ergir, Ece, Oliver-De La Cruz, Jorge, Fernandes, Soraia, Cassani, Marco, Niro, Francesco, Pereira-Sousa, Daniel, Vrbský, Jan, Vinarský, Vladimír, Perestrelo, Ana Rubina, Debellis, Doriana, Vadovičová, Natália, Uldrijan, Stjepan, Cavalieri, Francesca, Pagliari, Stefania, Redl, Heinz, Ertl, Peter, Forte, Giancarlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579206/
https://www.ncbi.nlm.nih.gov/pubmed/36257968
http://dx.doi.org/10.1038/s41598-022-22225-w