cccDNA Surrogate MC-HBV–Based Screen Identifies Cohesin Complex as a Novel HBV Restriction Factor

BACKGROUND & AIMS: Covalently closed circular DNA (cccDNA) of hepatitis B virus (HBV), existing as a stable minichromosome in the hepatocyte, is responsible for persistent HBV infection. Maintenance and sustained replication of cccDNA require its interaction with both viral and host proteins. Ho...

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Detalles Bibliográficos
Autores principales: Wu, Zhuanchang, Wang, Liyuan, Wang, Xin, Sun, Yang, Li, Haoran, Zhang, Zhaoying, Ren, Caiyue, Zhang, Xiaohui, Li, Shuangjie, Lu, Jinghui, Xu, Leiqi, Yue, Xuetian, Hong, Yue, Li, Qiang, Zhu, Haizhen, Gong, Yaoqin, Gao, Chengjiang, Hu, Huili, Gao, Lifen, Liang, Xiaohong, Ma, Chunhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579331/
https://www.ncbi.nlm.nih.gov/pubmed/35987451
http://dx.doi.org/10.1016/j.jcmgh.2022.08.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579331/
https://www.ncbi.nlm.nih.gov/pubmed/35987451
http://dx.doi.org/10.1016/j.jcmgh.2022.08.002

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