Cargando…
cccDNA Surrogate MC-HBV–Based Screen Identifies Cohesin Complex as a Novel HBV Restriction Factor
BACKGROUND & AIMS: Covalently closed circular DNA (cccDNA) of hepatitis B virus (HBV), existing as a stable minichromosome in the hepatocyte, is responsible for persistent HBV infection. Maintenance and sustained replication of cccDNA require its interaction with both viral and host proteins. Ho...
Autores principales: | Wu, Zhuanchang, Wang, Liyuan, Wang, Xin, Sun, Yang, Li, Haoran, Zhang, Zhaoying, Ren, Caiyue, Zhang, Xiaohui, Li, Shuangjie, Lu, Jinghui, Xu, Leiqi, Yue, Xuetian, Hong, Yue, Li, Qiang, Zhu, Haizhen, Gong, Yaoqin, Gao, Chengjiang, Hu, Huili, Gao, Lifen, Liang, Xiaohong, Ma, Chunhong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579331/ https://www.ncbi.nlm.nih.gov/pubmed/35987451 http://dx.doi.org/10.1016/j.jcmgh.2022.08.002 |
Ejemplares similares
-
Minicircle HBV cccDNA with a Gaussia luciferase reporter for investigating HBV cccDNA biology and developing cccDNA-targeting drugs
por: Li, Feng, et al.
Publicado: (2016) -
The Role of cccDNA in HBV Maintenance
por: Allweiss, Lena, et al.
Publicado: (2017) -
HBV cccDNA: The Stumbling Block for Treatment of HBV Infection
por: Liu, Shousheng, et al.
Publicado: (2019) -
Mapping the Interactions of HBV cccDNA with Host Factors
por: Mohd-Ismail, Nur K., et al.
Publicado: (2019) -
Gene Editing Technologies to Target HBV cccDNA
por: Martinez, Maria Guadalupe, et al.
Publicado: (2022)