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A longitudinal study of cytochrome P450 2D6 (CYP2D6) activity during adolescence

CYP2D6 substrates are among the most highly prescribed medications in teenagers and also commonly associated with serious adverse events. To investigate the relative contributions of genetic variation, growth, and development on CYP2D6 activity during puberty, healthy children and adolescents 7–15 y...

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Detalles Bibliográficos
Autores principales: Leeder, J. Steven, Gaedigk, Andrea, Wright, Krista J., Staggs, Vincent S., Soden, Sarah E., Lin, Yvonne S., Pearce, Robin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579386/
https://www.ncbi.nlm.nih.gov/pubmed/35997001
http://dx.doi.org/10.1111/cts.13380