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A phase I study comparing the pharmacokinetics of the biosimilar (RD12014) with liraglutide (Victoza) in healthy Chinese male subjects

This study aimed to evaluate the pharmacokinetics (PKs), safety, and immunogenicity of the biosimilar (RD12014) compared to reference liraglutide (Victoza) in healthy Chinese male subjects, so as to provide the basis for the similarity evaluation of the two drugs. Eligible subjects were randomized 1...

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Detalles Bibliográficos
Autores principales: Zhou, Ruirui, Guo, Linfeng, Gao, Xianglei, Wang, Yijun, Xu, Wenjing, Zou, Yang, Li, Wenjia, Zhuang, Yulei, Liu, Gangyi, Liu, Yanmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579399/
https://www.ncbi.nlm.nih.gov/pubmed/35871497
http://dx.doi.org/10.1111/cts.13374