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DNA 6mA Demethylase ALKBH1 Orchestrates Fatty Acid Metabolism and Suppresses Diet-Induced Hepatic Steatosis

BACKGROUND & AIMS: Nonalcoholic fatty liver disease (NAFLD) is a major cause of liver-related morbidity and mortality whereas the pathogenic mechanism remains largely elusive. DNA N6-methyladenosine (6mA) modification is a recently identified epigenetic mark indicative of transcription in eukary...

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Detalles Bibliográficos
Autores principales: Luo, Liping, Liu, Ya, Nizigiyimana, Paul, Ye, Mingsheng, Xiao, Ye, Guo, Qi, Su, Tian, Luo, Xianghang, Huang, Yan, Zhou, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579408/
https://www.ncbi.nlm.nih.gov/pubmed/36058506
http://dx.doi.org/10.1016/j.jcmgh.2022.08.011