The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance

The generation of mature T cells and establishment of central tolerance is predominantly orchestrated by thymic epithelial cells (TECs). Proprotein convertases are responsible for the proteolysis of proproteins into their mature bioactive counterparts. Here, we found that Furin, a member of the subt...

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Detalles Bibliográficos
Autores principales: Liang, Zhanfeng, Zhang, Zhaoqi, Zhang, Qian, Dong, Xue, Yang, Xiaofeng, Zhang, Jiayu, Lei, Tong, Creemers, John W.M., Zhang, Baojun, Zhao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579486/
https://www.ncbi.nlm.nih.gov/pubmed/36274943
http://dx.doi.org/10.1016/j.isci.2022.105233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579486/
https://www.ncbi.nlm.nih.gov/pubmed/36274943
http://dx.doi.org/10.1016/j.isci.2022.105233

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