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Vitamin D(3) alters macrophage phenotype and endosomal trafficking markers in dairy cattle naturally infected with Mycobacterium avium subsp. paratuberculosis

Macrophages are important host defense cells in ruminant paratuberculosis (Johne’s Disease; JD), a chronic enteritis caused by Mycobacterium avium subsp. paratuberculosis (MAP). Classical macrophage functions of pathogen trafficking, degradation, and antigen presentation are interrupted in mycobacte...

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Detalles Bibliográficos
Autores principales: Wherry, Taylor L. T., Dassanayake, Rohana P., Bannantine, John P., Mooyottu, Shankumar, Stabel, Judith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579537/
https://www.ncbi.nlm.nih.gov/pubmed/36275033
http://dx.doi.org/10.3389/fcimb.2022.1021657