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Comparative analysis of the repertoire of insulin-reactive B cells in type 1 diabetes-prone and resistant mice

Seropositivity for autoantibodies against multiple islet antigens is associated with development of autoimmune type 1 diabetes (T1D), suggesting a role for B cells in disease. The importance of B cells in T1D is indicated by the effectiveness of B cell-therapies in mouse models and patients. B cells...

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Detalles Bibliográficos
Autores principales: Banach, Maureen, Harley, Isaac T. W., Getahun, Andrew, Cambier, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579539/
https://www.ncbi.nlm.nih.gov/pubmed/36275764
http://dx.doi.org/10.3389/fimmu.2022.961209