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Comparative analysis of the repertoire of insulin-reactive B cells in type 1 diabetes-prone and resistant mice
Seropositivity for autoantibodies against multiple islet antigens is associated with development of autoimmune type 1 diabetes (T1D), suggesting a role for B cells in disease. The importance of B cells in T1D is indicated by the effectiveness of B cell-therapies in mouse models and patients. B cells...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579539/ https://www.ncbi.nlm.nih.gov/pubmed/36275764 http://dx.doi.org/10.3389/fimmu.2022.961209 |