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Role of C-terminal domain of Mycobacterium tuberculosis PE6 (Rv0335c) protein in host mitochondrial stress and macrophage apoptosis

PE/PPE proteins of Mycobacterium tuberculosis (Mtb) target the host organelles to dictate the outcome of infection. This study investigated the significance of PE6/Rv0335c protein's unique C-terminal in causing host mitochondrial perturbations and apoptosis. In-silico analysis revealed that sim...

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Detalles Bibliográficos
Autores principales: Medha, Priyanka, Bhatt, Parul, Sharma, Sadhna, Sharma, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579591/
https://www.ncbi.nlm.nih.gov/pubmed/36258102
http://dx.doi.org/10.1007/s10495-022-01778-1