Cargando…

Role of C-terminal domain of Mycobacterium tuberculosis PE6 (Rv0335c) protein in host mitochondrial stress and macrophage apoptosis

PE/PPE proteins of Mycobacterium tuberculosis (Mtb) target the host organelles to dictate the outcome of infection. This study investigated the significance of PE6/Rv0335c protein's unique C-terminal in causing host mitochondrial perturbations and apoptosis. In-silico analysis revealed that sim...

Descripción completa

Detalles Bibliográficos
Autores principales:	Medha, Priyanka, Bhatt, Parul, Sharma, Sadhna, Sharma, Monika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579591/ https://www.ncbi.nlm.nih.gov/pubmed/36258102 http://dx.doi.org/10.1007/s10495-022-01778-1

Ejemplares similares

Mycobacterium tuberculosis Protein PE6 (Rv0335c), a Novel TLR4 Agonist, Evokes an Inflammatory Response and Modulates the Cell Death Pathways in Macrophages to Enhance Intracellular Survival
por: Sharma, Neha, et al.
Publicado: (2021)

Prediction and identification of T cell epitopes of COVID-19 with balanced cytokine response for the development of peptide based vaccines
por: Medha, et al.
Publicado: (2021)

The Mycobacterium tuberculosis PE Proteins Rv0285 and Rv1386 Modulate Innate Immunity and Mediate Bacillary Survival in Macrophages
por: Tiwari, Bhavana Mishra, et al.
Publicado: (2012)

Secreted Mycobacterium tuberculosis Rv3654c and Rv3655c Proteins Participate in the Suppression of Macrophage Apoptosis
por: Danelishvili, Lia, et al.
Publicado: (2010)

Evaluation of Rv0220, Rv2958c, Rv2994 and Rv3347c of Mycobacterium tuberculosis for serodiagnosis of tuberculosis
por: You, Xiaolong, et al.
Publicado: (2017)

Mycobacterium tuberculosis Rv0366c-Rv0367c encodes a non-canonical PezAT-like toxin-antitoxin pair
por: Tandon, Himani, et al.
Publicado: (2019)

PE11 (Rv1169c) selectively alters fatty acid components of Mycobacterium smegmatis and host cell interleukin-6 level accompanied with cell death
por: Deng, Wanyan, et al.
Publicado: (2015)

PGRS Domain of Rv0297 of Mycobacterium tuberculosis Is Involved in Modulation of Macrophage Functions to Favor Bacterial Persistence
por: Sharma, Tarina, et al.
Publicado: (2020)

Triclosan-induced genes Rv1686c-Rv1687c and Rv3161c are not involved in triclosan resistance in Mycobacterium tuberculosis
por: Gomez, Andromeda, et al.
Publicado: (2016)

The PGRS Domain of Mycobacterium tuberculosis PE_PGRS Protein Rv0297 Is Involved in Endoplasmic Reticulum Stress-Mediated Apoptosis through Toll-Like Receptor 4
por: Grover, Sonam, et al.
Publicado: (2018)

The PE16 (Rv1430) of Mycobacterium tuberculosis Is an Esterase Belonging to Serine Hydrolase Superfamily of Proteins
por: Sultana, Rafiya, et al.
Publicado: (2013)

Rv3722c Promotes Mycobacterium tuberculosis Survival in Macrophages by Interacting With TRAF3
por: Lei, Yingying, et al.
Publicado: (2021)

Rv0180c contributes to Mycobacterium tuberculosis cell shape and to infectivity in mice and macrophages
por: Payros, Delphine, et al.
Publicado: (2021)

Investigation of the Rv3065, Rv2942, Rv1258c, Rv1410c, and Rv2459 efflux pump genes expression among multidrug-resistant Mycobacterium tuberculosis clinical isolates
por: Shahi, Fatemeh, et al.
Publicado: (2021)

Humoral Responses to Rv1733c, Rv0081, Rv1735c, and Rv1737c DosR Regulon-Encoded Proteins of Mycobacterium tuberculosis in Individuals with Latent Tuberculosis Infection
por: Kimuda, Simon G., et al.
Publicado: (2017)

Antigens Rv0310c and Rv1255c are promising novel biomarkers for the diagnosis of Mycobacterium tuberculosis infection
por: Luo, Liulin, et al.
Publicado: (2017)

Rv2031c of Mycobacterium tuberculosis: a master regulator of Rv2028–Rv2031 (HspX) operon
por: Mushtaq, Khurram, et al.
Publicado: (2015)

Molecular mechanism of interaction of Mycobacterium tuberculosis with host macrophages under high glucose conditions
por: Kundu, Jyoti, et al.
Publicado: (2021)

Functional Characterization of PknI-Rv2159c Interaction in Redox Homeostasis of Mycobacterium tuberculosis
por: Venkatesan, Arunkumar, et al.
Publicado: (2016)

PGRS Domain of Rv0297 of Mycobacterium tuberculosis Functions in A Calcium Dependent Manner
por: Sharma, Tarina, et al.
Publicado: (2021)

Structural and Functional Characterization of Rv0792c from Mycobacterium tuberculosis: Identifying Small Molecule Inhibitor against HutC Protein
por: Chauhan, Neeraj Kumar, et al.
Publicado: (2022)

The C-Terminal Domain of the Arabinosyltransferase Mycobacterium tuberculosis EmbC Is a Lectin-Like Carbohydrate Binding Module
por: Alderwick, Luke J., et al.
Publicado: (2011)

MiaA (Rv2727c) mediated tRNA isopentenylation of Mycobacterium tuberculosis H37Rv
por: Soman, Smitha, et al.
Publicado: (2022)

The N-terminal domain of Mycobacterium tuberculosis PPE17 (Rv1168c) protein plays a dominant role in inducing antibody responses in active TB patients
por: Abraham, Philip Raj, et al.
Publicado: (2017)

Mycobacterium tuberculosis Rv3160c is a TetR-like transcriptional repressor that regulates expression of the putative oxygenase Rv3161c
por: Tükenmez, Hasan, et al.
Publicado: (2021)

Biochemical characterization of PE_PGRS61 family protein of Mycobacterium tuberculosis H(37)Rv reveals the binding ability to fibronectin
por: Monu,, et al.
Publicado: (2016)

Comparative genomic and proteomic analyses of PE/PPE multigene family of Mycobacterium tuberculosis H(37)Rv and H(37)Ra reveal novel and interesting differences with implications in virulence
por: Kohli, Sakshi, et al.
Publicado: (2012)

Mycobacterium tuberculosis Rv2882c Protein Induces Activation of Macrophages through TLR4 and Exhibits Vaccine Potential
por: Choi, Han-Gyu, et al.
Publicado: (2016)

PE11, a PE/PPE family protein of Mycobacterium tuberculosis is involved in cell wall remodeling and virulence
por: Singh, Parul, et al.
Publicado: (2016)

The Mycobacterium tuberculosis PE_PGRS Protein Family Acts as an Immunological Decoy to Subvert Host Immune Response
por: Sharma, Tarina, et al.
Publicado: (2022)

Characterization of a Novel Esterase Rv0045c from Mycobacterium tuberculosis
por: Guo, Jiubiao, et al.
Publicado: (2010)

Mycobacterium tuberculosis Rv0991c Is a Redox-Regulated Molecular Chaperone
por: Becker, Samuel H., et al.
Publicado: (2020)

Prophage Gene Rv2650c Enhances Intracellular Survival of Mycobacterium smegmatis
por: Fan, Xiangyu, et al.
Publicado: (2022)

Deletion of Rv2571c Confers Resistance to Arylamide Compounds in Mycobacterium tuberculosis
por: Shelton, Catherine D., et al.
Publicado: (2021)

Modulation of the Activity of Mycobacterium tuberculosis LipY by Its PE Domain
por: Garrett, Christopher K., et al.
Publicado: (2015)

Mycobacterium tuberculosis Rv2005c Induces Dendritic Cell Maturation and Th1 Responses and Exhibits Immunotherapeutic Activity by Fusion with the Rv2882c Protein
por: Back, Yong Woo, et al.
Publicado: (2020)

Mycobacterium tuberculosis AtsG (Rv0296c), GlmU (Rv1018c) and SahH (Rv3248c) Proteins Function as the Human IL-8-Binding Effectors and Contribute to Pathogen Entry into Human Neutrophils
por: Dziadek, Bozena, et al.
Publicado: (2016)

Analysis of the noncoding RNA regulatory networks of H37Rv- and H37Rv△1759c-infected macrophages
por: Dong, Wenqi, et al.
Publicado: (2023)

Mycobacterium tuberculosis Rv0679c protein sequences involved in host-cell infection: Potential TB vaccine candidate antigen
por: Cifuentes, Diana P, et al.
Publicado: (2010)

Insights from the analysis of predicted Rv0679c protein peptide from Mycobacterium tuberculosis with Toll like Receptors in host
por: Lavarti, Rupa, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_79otq77q12hq05qmf5d23tvcli