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Comparison of blood and lymph node cells after intramuscular injection with HIV envelope immunogens
BACKGROUND: Harnessing CD4+ T cell help in the lymph nodes through rational antigen design could enhance formation of broadly neutralizing antibodies (bNAbs) during experimental HIV immunization. This process has remained hidden due to difficulty with direct study, with clinical studies instead focu...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579690/ https://www.ncbi.nlm.nih.gov/pubmed/36275655 http://dx.doi.org/10.3389/fimmu.2022.991509 |