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Multiomics data integration to reveal chromatin remodeling and reorganization induced by gene mutational synergy

Recurrent gene mutations often cooperate in a predefined stepwise and synergistic manner to alter global transcription, through directly or indirectly remodeling epigenetic landscape on linear and three-dimensional (3D) scales. Here, we present a multiomics data integration approach to investigate t...

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Detalles Bibliográficos
Autores principales: Yun, Haiyang, Vohra, Shabana, Lara-Astiaso, David, Huntly, Brian J.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579702/
https://www.ncbi.nlm.nih.gov/pubmed/36242770
http://dx.doi.org/10.1016/j.xpro.2022.101770