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Multiomics data integration to reveal chromatin remodeling and reorganization induced by gene mutational synergy
Recurrent gene mutations often cooperate in a predefined stepwise and synergistic manner to alter global transcription, through directly or indirectly remodeling epigenetic landscape on linear and three-dimensional (3D) scales. Here, we present a multiomics data integration approach to investigate t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579702/ https://www.ncbi.nlm.nih.gov/pubmed/36242770 http://dx.doi.org/10.1016/j.xpro.2022.101770 |