Inhibition of mitochondrial complex I leading to NAD(+)/NADH imbalance in type 2 diabetic patients who developed late stent thrombosis: Evidence from an integrative analysis of platelet bioenergetics and metabolomics

Type 2 diabetes mellitus (T2DM) is a strong indicator of late stent thrombosis (LST). Platelet bioenergetic dysfunction, although critical to the pathogenesis of diabetic macrovascular complications, remains uncharacterized in T2DM patients who developed LST. Here, we explored the mechanistic link b...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Mi-jie, Cui, Ning-hua, Liu, Xia'nan, Wang, Xue-bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579714/
https://www.ncbi.nlm.nih.gov/pubmed/36244294
http://dx.doi.org/10.1016/j.redox.2022.102507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579714/
https://www.ncbi.nlm.nih.gov/pubmed/36244294
http://dx.doi.org/10.1016/j.redox.2022.102507

Ejemplares similares