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Inhibition of mitochondrial complex I leading to NAD(+)/NADH imbalance in type 2 diabetic patients who developed late stent thrombosis: Evidence from an integrative analysis of platelet bioenergetics and metabolomics
Type 2 diabetes mellitus (T2DM) is a strong indicator of late stent thrombosis (LST). Platelet bioenergetic dysfunction, although critical to the pathogenesis of diabetic macrovascular complications, remains uncharacterized in T2DM patients who developed LST. Here, we explored the mechanistic link b...
Autores principales: | Gao, Mi-jie, Cui, Ning-hua, Liu, Xia'nan, Wang, Xue-bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579714/ https://www.ncbi.nlm.nih.gov/pubmed/36244294 http://dx.doi.org/10.1016/j.redox.2022.102507 |
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