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Peptide modified geniposidic acid targets bone and effectively promotes osteogenesis
BACKGROUND: Geniposidic acid (GPA), one of the active components of Eucommia ulmoides, promote bone formation and treat osteoporosis by activating farnesoid X receptor (FXR). However, GPA has low oral availability and lack of bone targeting in the treatment of bone related diseases. With the develop...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chinese Speaking Orthopaedic Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579733/ https://www.ncbi.nlm.nih.gov/pubmed/36313979 http://dx.doi.org/10.1016/j.jot.2022.07.007 |