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Peptide modified geniposidic acid targets bone and effectively promotes osteogenesis

BACKGROUND: Geniposidic acid (GPA), one of the active components of Eucommia ulmoides, promote bone formation and treat osteoporosis by activating farnesoid X receptor (FXR). However, GPA has low oral availability and lack of bone targeting in the treatment of bone related diseases. With the develop...

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Detalles Bibliográficos
Autores principales: Liu, Meijing, Zhu, Danqi, Jin, Fujun, Li, Shuang, Liu, Xiangning, Wang, Xiaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579733/
https://www.ncbi.nlm.nih.gov/pubmed/36313979
http://dx.doi.org/10.1016/j.jot.2022.07.007