Elizabethkingia Meningoseptica Infection in Neonates: Two Case Reports from the Eastern Region of Oman

Elizabethkingia meningoseptica is a gram-negative rod-shaped bacterium commonly found in soil and water. This organism is associated with nosocomial infections, especially in neonatal wards, as it has been isolated from contaminated medical equipment. Prompt diagnosis and early institution of appropriate combination therapy for prolonged period are crucial in the management of such infections. Herein, we describe two premature neonates admitted to our special care baby unit at 31 and 36 weeks old, respectively, who were diagnosed with neonatal bacterial sepsis. In both patients, blood and/or cerebrospinal fluid cultures indicated that E. meningoseptica was the causative organism. This bacterium is generally resistant to multiple antibiotics, including combination therapy. Therefore, E. meningoseptica can cause severe infection with a high risk of mortality and neurological sequelae in neonates. Intensive care and multidisciplinary interventions and involvement of an infection control team are crucial for effectively managing and preventing these infections.