Hepatic glycerol shunt and glycerol-3-phosphate phosphatase control liver metabolism and glucodetoxification under hyperglycemia

OBJECTIVE: Glycerol-3-phosphate (Gro3P) phosphatase (G3PP) hydrolyzes Gro3P to glycerol that exits the cell, thereby operating a “glycerol shunt”, a metabolic pathway that we identified recently in mammalian cells. We have investigated the role of G3PP and the glycerol shunt in the regulation of glu...

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Detalles Bibliográficos
Autores principales: Al-Mass, Anfal, Poursharifi, Pegah, Peyot, Marie-Line, Lussier, Roxane, Chenier, Isabelle, Leung, Yat Hei, Ghosh, Anindya, Oppong, Abel, Possik, Elite, Mugabo, Yves, Ahmad, Rasheed, Sladek, Robert, Murthy Madiraju, S.R., Al-Mulla, Fahd, Prentki, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579801/
https://www.ncbi.nlm.nih.gov/pubmed/36198384
http://dx.doi.org/10.1016/j.molmet.2022.101609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579801/
https://www.ncbi.nlm.nih.gov/pubmed/36198384
http://dx.doi.org/10.1016/j.molmet.2022.101609

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