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Orally administered antigen can reduce or exacerbate pathology in an animal model of inflammatory arthritis dependent upon the timing of administration

Currently, treatments for rheumatoid arthritis (RA) are focussed on management of disease symptoms rather than addressing the cause of disease, which could lead to remission and cure. Central to disease development is the induction of autoimmunity through a breach of self-tolerance. Developing appro...

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Detalles Bibliográficos
Autores principales: Meehan, Gavin R, Scales, Hannah E, McInnes, Iain B, Brewer, James M, Garside, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579813/
https://www.ncbi.nlm.nih.gov/pubmed/36268500
http://dx.doi.org/10.1093/immadv/ltac020