Class II transactivator induces expression of MHC-I and MHC-II in transmissible Tasmanian devil facial tumours

MHC-I and MHC-II molecules are critical components of antigen presentation and T cell immunity to pathogens and cancer. The two monoclonal transmissible devil facial tumours (DFT1, DFT2) exploit MHC-I pathways to overcome immunological anti-tumour and allogeneic barriers. This exploitation underpins...

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Detalles Bibliográficos
Autores principales: Ong, Chrissie E. B., Cheng, Yuanyuan, Siddle, Hannah V., Lyons, A. Bruce, Woods, Gregory M., Flies, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579919/
https://www.ncbi.nlm.nih.gov/pubmed/36259237
http://dx.doi.org/10.1098/rsob.220208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9579919/
https://www.ncbi.nlm.nih.gov/pubmed/36259237
http://dx.doi.org/10.1098/rsob.220208

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