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Traditional Chinese medicine based on Tongjiang methodology combined with proton pump inhibitor (PPI) step-down in treating non-erosive reflux disease: a study protocol for a multicentered, randomized controlled clinical trial

BACKGROUND: Non-erosive reflux disease (NERD) is characterized by typical gastroesophageal reflux symptoms, such as heartburn and regurgitation but an absence of esophageal mucosal damage during upper gastrointestinal endoscopy. Although proton pump inhibitors (PPIs) are the first line therapy, almo...

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Detalles Bibliográficos
Autores principales: Li, Xia, Wu, Haomeng, Zhang, Beihua, Chen, Ting, Shi, Xiaoshuang, Ma, Jinxin, Zhang, Jiaqi, Tang, Xudong, Wang, Fengyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580143/
https://www.ncbi.nlm.nih.gov/pubmed/36258217
http://dx.doi.org/10.1186/s13063-022-06811-x