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Circulating N-formylmethionine and metabolic shift in critical illness: a multicohort metabolomics study

BACKGROUND: Cell stress promotes degradation of mitochondria which release danger-associated molecular patterns that are catabolized to N-formylmethionine. We hypothesized that in critically ill adults, the response to N-formylmethionine is associated with increases in metabolomic shift-related meta...

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Detalles Bibliográficos
Autores principales: Sigurdsson, Martin Ingi, Kobayashi, Hirotada, Amrein, Karin, Nakahira, Kiichi, Rogers, Angela J., Pinilla-Vera, Mayra, Baron, Rebecca M., Fredenburgh, Laura E., Lasky-Su, Jessica A., Christopher, Kenneth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580206/
https://www.ncbi.nlm.nih.gov/pubmed/36261854
http://dx.doi.org/10.1186/s13054-022-04174-y